Housekeeping genes list. However, experimental support for .

Housekeeping genes list. However, experimental support for .

Housekeeping genes list. Jun 28, 2013 · Housekeeping genes are genes that are required for the maintenance of basal cellular functions that are essential for the existence of a cell, regardless of its specific role in the tissue or organism. Reference genes are assumed to be at a constant expression level, over a range of conditions such as temperature. Learn how to evaluate reference gene reliability across different tissues and conditions. This list provided in the link above is based on analysis of next-generation sequencing (RNA-seq) data. Using the optimized definition, we identify, characterize, and provide as resources, housekeeping gene lists extracted from several human datasets, and 10 other animal species that include primates, chicken, and C. Housekeeping genes are commonly described as “essential for cellular existence regardless of their specific function in the tissue or organism”, and “stably expressed irrespective of tissue type, developmental stage, cell cycle state, or external signal”. However, experimental support for Apr 29, 2025 · Optimize qPCR accuracy by selecting stable housekeeping genes. HRT Atlas also offers the most stable and suitable tissue selective candidate reference transcripts for normalization of qPCR experiments. [1] The database was constructed by mining more than 12000 human and mouse RNA-seq datasets. From a . We emphasize the importance of expres-sion at a constant level and provide a list of 3804 human genes that are expressed uniformly across a panel of tissues. com Here, we describe housekeeping gene detection in the era of massive parallel sequencing and RNA-seq. At least one variant of these genes is expressed in all tissues uniformly; see the above paper for details. Housekeeping genes are involved in basic cell maintenance and, therefore, are expected to maintain constant expression levels in all cells and conditions. Hounkpe et al. Identification of these genes facilitates exposure of the underlying cellular infrastructure and increases understanding of various structural ge … Jul 13, 2022 · The concept of “housekeeping gene” has been used for four decades but remains loosely defined. " For a more complete and updated list, see HRT Atlas database compiled by Bidossessi W. See full list on genomics-online. Jul 14, 2020 · User can visualize the expression and download lists of 2158 human HK transcripts from 2176 HK genes and 3024 mouse HK transcripts from 3277 mouse HK genes. Thus, they are expected to be expressed in all cells of an organism under normal conditions, irrespective of tissue type, developmental stage, cell cycle state, or external signal. The following is a partial list of "housekeeping genes. elegans. vwbb ckgggeq jhw oslbeasw qxxhdcgd uawy qnpcguh fuap cdc sigstpjaj